abstract：:Pathological alterations of capillaries, accelerated epidermopoesis, increased rate and extent of metabolism in the psoriatic lesion and first manifestation of psoriasis rarely in the first 20 years of life made us decide to investigate the human growth hormone (STH) in blood serum. In 70 patients suffering from psori...

journal_title：Archives of dermatological research

authors： Weber G,Neidhardt M,Schmidt A,Geiger A

更新日期：1981-01-01 00:00:00

abstract：:Female hairless mice (strain mutant hr/hr) have been irradiated with increasing doses of UV-B over a period of 4 weeks. They were compared with untreated controls Additional groups of 30 mice were treated with milk base or cream base or milk SPF6 or cream SPF6 or cream SPF8 daily before irradiation. No changes of body...

journal_title：Archives of dermatological research

authors： Vogel HG,Alpermann HG,Futterer E

更新日期：1981-01-01 00:00:00

abstract：:Exposure of hairless mice to the light of a germicidal lamp (254 nm) under conditions which are known to induce epidermal DNA synthesis, cell proliferation, and polyamine metabolism produced a marked increase of polyamine excretion in the urine which lasted for many days. The increase was about the same for free and a...

journal_title：Archives of dermatological research

authors： Seiler N,Richards W,Knödgen B

更新日期：1981-01-01 00:00:00

abstract：:Test results are reported of the effect of salicylic acid on the vasoconstrictive effect of flumethasone pivalate. In specific, the depigmentation of the skin (identical with increase in lightness of the skin) following topical application of flumethasone pivalate was investigated with the aid of an improved spectroph...

journal_title：Archives of dermatological research

authors： Wienert V,Blazek V

更新日期：1981-01-01 00:00:00

abstract：:Mycosis fungoides was observed in a 71-year-old male with Mediterranean lymphoma, a B-cell malignancy. It is proposed that this association is not incidental since hypergammaglobulinaemia and even monoclonal gammopathies have repeatedly been described in cutaneous T-cell lymphomas. Mediterranean lymphoma might have re...

journal_title：Archives of dermatological research

authors： Cassuto JP,Kövary PM,Campagni JP,Simony J,Maiolini R,Schneider M

更新日期：1981-01-01 00:00:00

abstract：:Recent studies on eosinophilic fasciitis have lead to this investigation of eosinophilia in progressive systemic sclerosis and localized scleroderma. Eosinophilia (eosinophilic count greater than 300/cmm) was found in ten of 63 progressive systemic sclerosis patients (15.8%) and in two of nine localized scleroderma ca...

journal_title：Archives of dermatological research

authors： Giordano M,Ara M,Valentini G,Chianese U,Bencivenga T

更新日期：1981-01-01 00:00:00

abstract：:Sixteen malignant melanoma patients with different levels of tumor progression, two patients with melanoma in situ (Clark 10 two bronchogenic carcinoma patients and nine healthy controls were tested by means of the leukocyte adherence inhibition (LAI) test to assess the function of their cellular mediated immunity. Bl...

journal_title：Archives of dermatological research

authors： Müller S,Ernst TM

更新日期：1980-01-01 00:00:00

abstract：:An aromatic retinoid (Ro 10-9359) in 13-cis retinoic acid (Ro 4-3780) were fed by gastric tube to 170 male adult Syrian hamsters daily for 30 days. A low dose of 1 or 2 mg/kg and a high dose of 20 mg/kg body weight were selected. The effects of both retinoids on the sebaceous glands were assessed planimetrically (15 g...

journal_title：Archives of dermatological research

authors： Plewig G

更新日期：1980-01-01 00:00:00

abstract：:To have as further insight into the localizations of immune deposits in the skin the reversed passive and the passive Arthus reactions were carried out in the foot-pads skin of guinea-pigs using horseradish peroxidase as antigen. The transient localizations of immune deposits in the papillary dermis and in the epiderm...

journal_title：Archives of dermatological research

authors： Ueki H,Nakaye M,Masuda T

更新日期：1980-01-01 00:00:00

abstract：:This study concerns 57 patients who fulfilled histological criteria for the diagnosis allergic vasculitis. For 37 of these patients, biopsy specimen were available from lesional and adjacent non-lesional skin. Histological signs of vasculitis were found at both sites, but in clinically normal skin the perivascular inf...

journal_title：Archives of dermatological research

authors： Herrmann WA,Kauffmann RH,van Es LA,Daha MR,Meijer CJ

更新日期：1980-01-01 00:00:00

abstract：:The prolongation of the S-phase, characteristic of psoriatic keratinocytes, can be observed in cells of the eccrine sweat glands as well as in those of the infundibular part of hair follicles. In healthy individuals the average duration of DNA-synthesis time (ts) in the cells of the hair follicle is 6.8 h, in unaffect...

journal_title：Archives of dermatological research

authors： Galosi A,Pullmann H,Steigleder GK

更新日期：1980-01-01 00:00:00

abstract：:The composition of the aerobic and anaerobic bacterial skin flora was investigated quantitatively and qualitatively in 25 patients with seborrheic eczema (SE) and in 35 healthy persons. In SE patients, the geometric mean count for propionibacteria in the pilosebaceous ducts of the forehead was reduced to a statistical...

journal_title：Archives of dermatological research

authors： Höffler U,Gloor M,Peters G,Ko HL,Bräutigan A,Thurn A,Pulverer G

更新日期：1980-01-01 00:00:00

abstract：:Acidic polysaccharides (AP) are released from Propionibacterium acnes I and II during growth. Similar antigens are released from two strains of P. avidum, but in a smaller amount. Furthermore, prostaglandin-like substances (PLS) have been isolated from the lipid fraction of P. acnes. The AP antigens give rise to a pre...

journal_title：Archives of dermatological research

authors： Dalen A,Hellgren L,Iversen OJ,Vincent J

更新日期：1980-01-01 00:00:00

abstract：:Forty-one male guinea pigs were treated orally with high doses of aromatic retinoid (Ro 10-9359) 25 mg/kg/day in oleum arachidis for 6 weeks. Twenty-three animals were investigated at the end of this treatment. The remaining 18 animals were investigated after an additional retinoid-free interval of 6 weeks. A control ...

journal_title：Archives of dermatological research

authors： Tsambaos D,Hundeiker M,Mahrle G,Orfanos CE

更新日期：1980-01-01 00:00:00

abstract：:Primary cultures of guinea pig ear keratinocytes were treated with vitamin A acid at plating, or at 14 h or 14 days after plating. The intracellular content of the cyclic nucleotides cAMP and cGMP was determined by radioimmunoassay at intervals during a period of 50 h after treatment. When added at plating, vitamin A ...

journal_title：Archives of dermatological research

authors： Wilkinson DI,Orenberg EK

更新日期：1980-01-01 00:00:00

abstract：:The effects of oral 8-methoxypsoralen-photochemotherapy (PUVA-therapy) on the inflammatory infiltrate in 14 psoriatic skin lesions and on normal skin of 7 controls were investigated by means of autoradiography and planimetry. Under PUVA-therapy, one finds a significant decrease in dermal cells per millimeter lesion in...

journal_title：Archives of dermatological research

authors： Landthaler M,Plewig G,Hofmann C,Braun-Falco O

更新日期：1980-01-01 00:00:00

abstract：:This study determines if the anatomic region affected percutaneous absorption in the rhesus monkey, an animal model with some relevance to man. Percutaneous absorption of testosterone (13.3 microgram/cm2) from the ventral forearm was 8.8 +/- 2.5%. Absorption from the chest was slightly less (5.3 +/- 0.6%) while that f...

journal_title：Archives of dermatological research

authors： Wester RC,Noonan PK,Maibach HI

更新日期：1980-01-01 00:00:00

abstract：:Vitiliginous patients undergoing photochemotherapy with TMP were less susceptible to a sun burn. To investigate this point, the MED for UV-B was measured before, 2 h, and 24 h after oral intake of TMP in 10 healthy volunteers. There was an increase of MED when UV exposure had taken place 2 h after TMP intake (P < 0.01...

journal_title：Archives of dermatological research

authors： Agache PG,Coupez L

更新日期：1980-01-01 00:00:00

abstract：:Three new cromones have been studied that are supposed to be better absorbed and to have a wider spectrum of anti-allergic activity than disodium cromoglycate. Pretreatment with i.d. injection of 10 microgram FPL 52758 significantly reduced the weal and flare reaction induced by specific antigen in 11 patients with at...

journal_title：Archives of dermatological research

authors： Søndergaard J,Kassis V,Knudsen L,Wadskov S,Wanscher B,Weismann K

更新日期：1980-01-01 00:00:00

abstract：:The mechanical properties of the in vivo dermis were measured by means of a torque applied to the skin. The resulting deformation of 2-6 degrees, including the immediate and delayed visco-elastic components, as well as the relaxation were measured, and the raw values corrected for a constant skin thickness. The experi...

journal_title：Archives of dermatological research

authors： Agache PG,Monneur C,Leveque JL,De Rigal J

更新日期：1980-01-01 00:00:00

abstract：:In 8 patients with idiopathic chronic urticaria suction blisters were produced simultaneously on lesional and perilesional skin in the periumbilical area without application of heat. The suction pressure was 250 mm Hg, and thus the blister production lasted from 60--120 min. The blister fluid histamine was determined ...

journal_title：Archives of dermatological research

authors： Bork K,König W,Böhm G

更新日期：1979-11-01 00:00:00

abstract：:The distribution coefficient of caffeine (water/n-Octanol) and the estimation of caffeine in urine after local application indicate to a high permeation rate of caffeine through the skin. This could be confirmed by using different vehicles in vivo and in vitro. 14C labeled caffeine penetrates rapidly the epidermis and...

journal_title：Archives of dermatological research

authors： Zesch A,Schaefer H,Stüttgen G

更新日期：1979-11-01 00:00:00

abstract：:An ultrastructural investigation of two cutaneous lesions in a two-year-old Turkish boy with disseminated lipogranulomatosis (Farber) revealed curvilinear bodies in fibroblasts, histiocytes, and endothelial cells; "elongated membranes" in fibroblasts and endothelial cells; "zebra bodies" in endothelial cells; and spin...

journal_title：Archives of dermatological research

authors： Schmoeckel C,Hohlfed M

更新日期：1979-10-01 00:00:00

abstract：:Electron microscopic aspects in ten cases of normolipidemic cutaneous xanthomatosis have been investigated. Two additional types IV and V hyperlipoproteinaemic xanthomatosis have also been included. Ultrastructural findings in all cases were similar. Abundant histiocytic cells with numerous intracytoplasmic lipid vacu...

journal_title：Archives of dermatological research

authors： Ferrando J,Bombi JA

更新日期：1979-10-01 00:00:00

abstract：:This study was designed to investigate the effects of griseofulvin, 5-fluorocytosine (5-FC), and amphotericin B on pancreatic and gastric secretion after the administration of a single large dose, or repeated small doses for 3 weeks, in male albino rats. The exocrine functions of the main digestive glands were only sl...

journal_title：Archives of dermatological research

authors： Park YK,Lee S,Kim WJ,Hong SS

更新日期：1979-10-01 00:00:00

abstract：:Dopamine causes reflex erythema, central blanching, and piloerection depending on the dose and the type of application wheal reaction. Intracutaneous application shows from 1.5 gamma/0.1 ml wheal formation, erythema, piloerection, and blanching combined with increased heat radiation from the skin surface (AGA thermovi...

journal_title：Archives of dermatological research

authors： Stüttgen G,Dreesen R

更新日期：1979-08-01 00:00:00

abstract：:Recently a new thin layer chromatography plate (Whatman LK 6D) became available which is extremely easy to handle and permits highly reproducible qualitative and quantitative analysis. This plate proved to be of great value for the investigation of skin surface lipids. The use of a fatty acid methyl ester as an intern...

journal_title：Archives of dermatological research

authors： Weissmann A

更新日期：1979-07-30 00:00:00

abstract：:This study was designed to investigate the proliferative activity of the buccal mucosa in healthy adult persons with regard to individual age. Punch biopsy specimens were taken from the buccal mucosa of 19 individuals (10 females, 9 males) ranging in age from 24 to 80 years, and were then examined autoradiographically...

journal_title：Archives of dermatological research

authors： Maidhof R,Hornstein OP

更新日期：1979-06-25 00:00:00

abstract：:The penetration through the epidermis in vitro of various topically used corticosteroids was compared. The amount penetrating through the epidermis from an ethanolic solution showed good correlation with the polarity of the corticosteroids under study. Hydrocortisone, the most polar corticosteroid, penetrates the epid...

journal_title：Archives of dermatological research

authors： Ponec M,Polano MK

更新日期：1979-05-29 00:00:00

abstract：:In a group of 40 patients suffering from wide-spread psoriasis oral administration of a retinoid (Ro 10-9359) was followed by PUVA therapy. The clearance rate was increased by 30% as compared to PUVA alone. Except for cheilitis no side effects were seen. Histological analysis in 20 patients before, during and after th...

journal_title：Archives of dermatological research

authors： Heidbreder G,Christophers E

更新日期：1979-05-04 00:00:00

abstract：:In a previous study, impedance measurements and phoreographic response were shown to quantify significant differences between involved and non-involved skin in psoriasis. The same techniques were used to objectivate the evolution on skin condition on patients treated with dioxyanthranol, difluprednate, and photochemot...

journal_title：Archives of dermatological research

authors： Cambrai M,Clar EJ,Grosshans E,Altermatt C

更新日期：1979-03-31 00:00:00

abstract：:The dependence of epithelial spread on human serum in culture has been studied. Using measured pieces of mouse ear skin epithelial outgrowth about floating explants (epiboly) and from adherent explants was studied. Where compared directly the two systems show similar results. Because of its ease of quantitation, the a...

journal_title：Archives of dermatological research

authors： Stenn KS,Dvoretzky I

更新日期：1979-02-23 00:00:00

abstract：:Tumor-associated antigens were demonstrated in phenol water extracts of human malignant melanoma by migration tests with leukocytes from melanoma patients and controls: in 25 out of 60 melanoma patients weak reactivity was observed, usually stimulation of leukocyte migration, while leukocytes from 37 controls were neg...

journal_title：Archives of dermatological research

authors： Suter L,Tilkorn H,Kövary PM

更新日期：1979-02-23 00:00:00

abstract：:1. Suction blisters on the skin of rats, obtained with a negative pressure of 150 mm Hg, show a close similarity to human suction blisters, based on histological, electrolyte and protein findings. 2. Pharmacokinetic experiments with inulin and antipyrine have proved that the movement of these low protein binding drugs...

journal_title：Archives of dermatological research

authors： Herfst MJ,van Rees H

更新日期：1978-12-01 00:00:00

abstract：:A 61-year old woman developed a tumourous nodule in her left leg. Fifteen years ago a similar tumour had been removed in the same localization. Histological examination performed on biopsy material showed bundles of predominantly fusiform tumour cells with nuclear pleomorphism and many mitotic figures. Electron micros...

journal_title：Archives of dermatological research

authors： Seifert HW

更新日期：1978-11-10 00:00:00

abstract：:The function of microphages has been studied in two patients with chronic pyoderma vegetans by in vitro determination of phagocytosis as well as chemotaxis. The results showed a striking decrease in the chemotactic activity of the neutrophil granulocytes, a reduced phagocytosis of Candida albicans and Staphylococcus a...

journal_title：Archives of dermatological research

authors： Djawari D,Hornstein OP

更新日期：1978-09-28 00:00:00

abstract：:The authors report 2 cases of atypical vitiligo in which they observed 1) "cockade-like" lesions resembling those of "trichrome" vitiligo (from the centre to the periphery, achromic area, hypochromic ring, normal or hyperchromic border), 2) numerous linear achromic lesions corresponding to former excoriations (Koebner...

journal_title：Archives of dermatological research

authors： Dupré A,Christol B

更新日期：1978-07-28 00:00:00

abstract：:The pathomorphological and pathophysiological reactions of the first skincycle of the mutant (Ng) were histologically investigated. 1. During the hair growth disturbances as the result of imperfect keratinisation changes of the morphology and function of different skin areas could be observed. 2. The developments of a...

journal_title：Archives of dermatological research

authors： Franz E,Bosse K,Kreutzer E

更新日期：1978-06-29 00:00:00

abstract：:In order to find, whether 8-MOP has an inhibiting effect on the proliferation of lymphocytes in the dark, we studied in vitro the lymphocyte proliferation by a mitogen (HgCl2) and by an antigen (tuberculin) from 16 psoriatic patients during the first oral PUVA treatment immediately before 8-MOP intake (03.--0.5 mg/kg ...

journal_title：Archives of dermatological research

authors： Lischka G,Decker E

更新日期：1978-05-31 00:00:00

abstract：:Human skin epithelial-like cells (NCTC strain 2544) were grown in NCTC 135 medium. Neuraminidase and hyaluronidase were added to the growth medium. Cells were incubated 96 h at 36 degrees C. Growth rate and viscosity of cell suspensions were measured after forming single cells mechanically (mopping). With addition of ...

journal_title：Archives of dermatological research

authors： Neufahrt A,Förster FJ,Gottschalk K,Leonhardi G

更新日期：1978-02-15 00:00:00